Beta Cyclodextrin USP

Beta-cyclodextrin USP (United States Pharmacopeia) refers to a specific form of the cyclodextrin molecule known as beta-cyclodextrin, which meets the quality and purity standards outlined in the United States Pharmacopeia. Beta-cyclodextrin is a cyclic oligosaccharide composed of seven glucose units linked together in a torus (doughnut) shape.

Cyclodextrins are widely used in the pharmaceutical industry due to their ability to form inclusion complexes with various guest molecules. The hydrophobic cavity of the cyclodextrin can encapsulate hydrophobic or poorly soluble molecules, thereby improving their solubility, stability, and bioavailability. This property makes cyclodextrins valuable in drug formulation and delivery.

When a cyclodextrin meets the requirements set by the United States Pharmacopeia, it signifies that it has been thoroughly tested and verified to meet certain standards of identity, strength, quality, and purity. This ensures that the beta-cyclodextrin is suitable for use in pharmaceutical applications and that it adheres to the regulatory standards necessary for drug development and manufacturing.

Beta-cyclodextrin USP can be used in various pharmaceutical formulations, such as oral tablets, capsules, liquid solutions, and topical preparations, to enhance the solubility and bioavailability of active pharmaceutical ingredients (APIs) that have low water solubility. It can also be used in other applications, such as in the food and cosmetic industries.

The USP monograph for beta-cyclodextrin provides detailed information about its specifications, tests, and acceptance criteria, ensuring consistency and quality in pharmaceutical products that utilize this ingredient.